OVARIAN SUPPORT OF PREGNANCY IN AGEING INBRED MICE

Pregnancy Rate Following Luteal Phase Support in Iranian Women with Polycystic Ovarian Syndrome

Biomarkers of Ovarian Ageing

The ovary is the main regulator of female fertility, and its biologic clock is set to ensure reproductive success during a definite life stage. According to the evolutionary concept that organisms maximize fitness by promoting production of progeny, allocation of resources between reproductive and somatic functions is finely regulated during life [1]. Thus, it has been speculated that the prema...

Endothelial Vasodilator Angiotensin Receptors are Changing in Mice with Ageing

Background: The vascular function of Angiotensin II-type-2 receptors in adults is controversial. We sought their location and function in mouse aortic rings at young and old mice. Materials and Methods: Male C57Bl mice (aged 4 and 14 months) were killed by CO2. The descending thoracic aorta was cleaned and dissected into rings. Aortic rings were mounted in Krebs’ solution at 37 °C an...

Influence of the genotype of males on pregnancy-block in inbred mice.

Variations in the incidence of pregnancy-block (Bruce effect) dependent on the genotype of the male were recorded in female mice belonging to two inbred strains. CBA females invariably responded with a high rate of return of oestrus irrespective of the blocking agent, KE and CBA males, or spayed and masculinized females belonging to these two strains. By contrast, KE females only react strongly...

Quantitative genetics of sleep in inbred mice

The timing and the organization of sleep architecture are mainly controlled by the circadian system, while sleep need and intensity are regulated by a homeostatic process. How independent these two systems are in regulating sleep is not well understood. In contrast to the impressive progress in the molecular genetics of circadian rhythms, little is known about the molecular basis of sleep. Neve...